VHP空间灭菌技术在CAR-T细胞生产中的应用

2020-05-24

近年来，细胞治疗产品，尤其是嵌合抗原受体T细胞（CAR-T）的研发与临床应用发展迅猛。在美国临床试验网站检索全球CAR-T细胞治疗临床试验登记数可以发现，中国所登记的项目数仅次于美国，居全球第二。迄今为止，国内已有近二十家公司拿到了CAR-T细胞疗法的临床批件[1]。

微生物监测在生物安全实验室中的一种应用

2020-03-19

疾控中心的建设要符合我国现行的生物安全实验室各项标准，目前国际上依据实验室所处理对象的生物危险程度，把生物安全实验室分为四级：一级对生物安全隔离的要求最低，四级最高。我国目前有两个四级生物安全实验室：湖北武汉BSL-4病毒实验室（中国科学院武汉国家生物安全实验室 ）和国家动物疫病防控高级别生物安全实验室（中国农业科学院哈尔滨兽医研究所）。

Simply Good Monitoring

2020-03-10

Digitising process development can reduce the time delay between sampling and availability, and can increase the quality of the data obtained

Lucullus PIMS for event-based process control

2020-03-10

Process control is a central task in bioprocess development and production. Apart from common control tasks including pH, temperature or dissolved oxygen, more advanced control tasks must be mastered. Real-time availability of analytical data is ofte

Automated bioreactor sampling for on-line analysis of amino acids using two approaches: HPLC and Cedex® Bio HT Analyzer

2020-03-10

To facilitate optimal process control limiting substrates must be identified, moni-tored and controlled. Amino acids are often critical substances, especially in mam-malian processes. Measurement and thus monitoring is tedious and rarely done.